Лувомеран

Rec. INN (наименование, зарегистрированное ВОЗ)

2845125-98-4

messenger RNA (mRNA), 5' capped, encoding codon- optimised human cystic fibrosis transmembrane conductance regulator (hCFTR; channel conductance- controlling ATPase, cAMP-dependent chloride channel, ATP-binding cassette sub-family C member 7), flanked by 5' and 3' untranslated regions based on the Mus musculus histone H1.5 gene and the human haemoglobin subunit alpha (HBA1) gene, followed by a 3' polyadenylation (polyA) tail (containing a 100- nucleotide polyA sequence, a 5-nucleotide XbaI scar and a 20-nucleotide polyA sequence ending with an inverted dT); contains N¹-methylpseudouridine instead of uridine (all-U>m¹Ψ)

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