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Rec. INN (наименование, зарегистрированное ВОЗ)

2640223-84-1

immunoglobulin G1-lambda, anti-[severe acute respiratory syndrome (human) coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein, receptor binding domain (RBD)], Homo sapiensmonoclonal antibody;
gamma1 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV3-30*01 (96.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1, G1v14 CH2 A1.3, A1.2, G1v24 CH3 L107, S114 (CH1 R120>K (217) (121-218), hinge 1- 15 (219-233), CH2 L1.3>A (237), L1.2>A (238), P114>G (332) (234-343), CH3 E12 (359), M14 (361), M107>L (431), N114>S (437) (344-448), CHS (449-450)) (121-450)], (223-215')-disulfide with lambda light chain Homo sapiens (1'-216') [V-LAMBDA (Homo sapiens IGLV2-14*03 (94.9%) -IGLJ3*02 (100%), CDR- IMGT [9.3.10] (26-34.52-54.91-100)) (1'-110') -Homo sapiens IGLC1*02 (100%) (111'-216')]; dimer (229-229'':232-232'')- bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV lacking the glutamine synthetase (GS-KO) gene, glycoform alfa

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