Мавростобарт

Prop. INN (наименование, предложенное ВОЗ)

2928515-12-0

Immunoglobulin G4-kappa, anti-[Homo sapiens NT5E (5'-nucleotidase ecto, 5'-nucleotidase, NT5, eN, eNT, NTE, CALJA, CD73)];
H-gamma4 heavy chain (1-448) [VH Musmus/Homsap (Mus musculus IGHV1-80*01 (77.6%) -(IGHD) -IGHJ3*01 (85.7%) A128>S (121)/Homo sapiens IGHV3-66*01 (71.4%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (122-219), hinge 1-12 S10>P (229) (220-231), CH2 L92 (310) (232-341), CH3 (342-446), CHS (447-448)) (122-448)], (135-220')-disulfide with L-kappa light chain (1'-220') [V-KAPPA Musmus/Homsap (Mus musculus IGKV8-24*01 (86.1%) -(IGHD) -IGHJ5*01 (91.7%) L126>I (112')/Homo sapiens IGKV4-1*01 (80.2%) -(IGHD) -IGHJ2*01 (90.9%) Q120>A (106'), CDR-IMGT [12.3.9] (27'-38'.56'-58'.95'-103')) (1'-113') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (159'), V101 (197')) (114'-220')]; dimer (227-227'':230-230'')-bisdisulfide, produced in a cell line from Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, glycoform alfa

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