Мазорелвимаб
MazorelvimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2419087-89-9
Химическое название
immunoglobulin G1-kappa, anti-[rabies lyssavirus (rabies virus, RABV) spike glycoprotein G], monoclonal antibody;
gamma1 heavy chain (1-450) [VH (Homo sapiens IGHV3-48*03 (85.7%) -(IGHD) -IGHJ4*01 (92.3%) L123>M (115), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (217) (121-218), hinge 1-15 (219-233), CH2 (234-343), CH3 D12 (359), L14 (361) (344-448), CHS (449-450)) (121-450)], (223-219')-disulfide with kappa light chain (1'-219') [V-KAPPA Musmus/Homsap (Mus musculus IGKV1-99*01 (92.0%) -IGKJ1*02 (90.0%) L124>V (109)/Homo sapiens IGKV2D-29*02 (88.0%) -IGKJ4*01 (91.7%), CDR-IMGT [11.3.9] (27-37.55-57.94-102)) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (229-229'':232-232'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-DG44 cell line, glycoform alfa
gamma1 heavy chain (1-450) [VH (Homo sapiens IGHV3-48*03 (85.7%) -(IGHD) -IGHJ4*01 (92.3%) L123>M (115), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (217) (121-218), hinge 1-15 (219-233), CH2 (234-343), CH3 D12 (359), L14 (361) (344-448), CHS (449-450)) (121-450)], (223-219')-disulfide with kappa light chain (1'-219') [V-KAPPA Musmus/Homsap (Mus musculus IGKV1-99*01 (92.0%) -IGKJ1*02 (90.0%) L124>V (109)/Homo sapiens IGKV2D-29*02 (88.0%) -IGKJ4*01 (91.7%), CDR-IMGT [11.3.9] (27-37.55-57.94-102)) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (229-229'':232-232'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-DG44 cell line, glycoform alfa
Структура
Иностранные названия
- Mazorelvimabum (латинское)
- Mazorelvimab (английское)
- Mazorelvimab (немецкое)
- Mazorelvimab (французское)
- Mazorelvimab (испанское)
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