Миситатуг

Prop. INN (наименование, предложенное ВОЗ)

2767203-01-8

immunoglobulin G1-kappa, anti-[Homo sapiens MSLN (mesothelin, pre-pro-megakaryocyte-potentiating factor, megakaryocyte-potentiating factor, MPF, CAK1)];
H-gamma1 heavy chain (1-454) [VH Musmus/Homsap (Mus musculus IGHV4-1*02 (91.8%) -(IGHD) -IGHJ1*01 (100%)/Homo sapiens IGHV3-74*03 (80.6%) -(IGHD) -IGHJ3*01 (85.7%) Q120>A (116), M123>T (119), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1 R120>K (221) (125-222), hinge 1-15 (223-237), CH2 (238-347), CH3 E12 (363), M14 (365) (348-452), CHS (453-454)) (125-454)], (227-213')-disulfide with L-kappa light chain (1'-213') [V-KAPPA Musmus/Homsap (Mus musculus IGKV4-55*01 (84.0%) -IGKJ1*01 (90.9%) L124>V (103)/Homo sapiens IGKV6-21*02 (68.4%) -IGKJ4*01 (100%), CDR-IMGT [5.3.9] (27'-31'.49'-51'.88'-96')) (1'-106') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (152'), V101 (190') (107'-213')]; dimer (233-233'':236-236'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

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