Моцемэстроцел

Rec. INN (наименование, зарегистрированное ВОЗ)

human culture expanded sub-fractionated allogeneic adherent mesenchymal-like stromal cells derived from bone marrow of healthy living donors. Cells express cell surface markers CD105, CD73, CD90 and human leukocyte antigen (HLA) class-I, and express transforming growth factor beta 1 (TGF-β1), soluble tumour necrosis factor receptor 1 (sTNF-R1), interleukin-10 (IL-10), interleukin 17 (IL-17), acetylcholine (ACh), ICOS ligand (B7 homolog 2, B7- H2, ICOSL, antigen CD275), and indoleamine 2,3- dioxygenase 1 (IDO-1). The cells are negative for CD34, CD45, CD14 and HLA-DR markers.

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