Монализумаб
MonalizumabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
Drugbank
DB12824
CAS
1228763-95-8
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens KLRC1 (killer cell lectin-like receptor subfamily C member 1, NKG2-A, NKG2A, CD159a, CD94)],humanized monoclonal antibody;
gamma4 heavy chain (1-452) [humanized VH (Homo sapiens IGHV1-18*01 (89.80%) -(IGHD)-IGHJ2*01 R120>Q (117), L123>T (130)) [8.8.18] (1-125)), IGHG4*01 (CH1 (126-223), hinge S10>P (233) (224-235), CH2 (236- 345), CH3 (346-450), CHS (451-452)) (126-452)], (139- 214')-disulfide with kappa light chain (1’-214’) [humanized V-KAPPA (Homo sapiens IGKV1-39*01 (87.40%) - IGKJ4*01) [6.3.9] (1'-107') -Homo sapiens IGKC*01, Km3 (108'-214')]; dimer (231-231":234-234")-bisdisulfide
gamma4 heavy chain (1-452) [humanized VH (Homo sapiens IGHV1-18*01 (89.80%) -(IGHD)-IGHJ2*01 R120>Q (117), L123>T (130)) [8.8.18] (1-125)), IGHG4*01 (CH1 (126-223), hinge S10>P (233) (224-235), CH2 (236- 345), CH3 (346-450), CHS (451-452)) (126-452)], (139- 214')-disulfide with kappa light chain (1’-214’) [humanized V-KAPPA (Homo sapiens IGKV1-39*01 (87.40%) - IGKJ4*01) [6.3.9] (1'-107') -Homo sapiens IGKC*01, Km3 (108'-214')]; dimer (231-231":234-234")-bisdisulfide
Структура
Иностранные названия
- Monalizumabum (латинское)
- Monalizumab (английское)
- Monalizumab (немецкое)
- Monalizumab (французское)
- Monalizumab (испанское)
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