Мозистобарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2852752-92-0

immunoglobulin G1-kappa, anti-[Homo sapiens CD22 (sialic acid binding Ig-like lectin 2, SIGLEC2, SIGLEC-2, B-lymphocyte cell adhesion molecule, BL-CAM, Leu-14)], humanized monoclonal antibody;
H-gamma1 heavy chain humanized (1-460) [VH (Homo sapiens IGHV3-48*03 (89.8%) -(IGHD) -IGHJ4*01 (85.7%) Q120>R (115), CDR-IMGT [8.8.16] (26-33.51-58.97-112)) (1-123) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14, G1v14-1 CH2 A1.3, A1.2, A1 (CH1 R120>K (220) (124-221), hinge 1-15 (222-236), CH2 L1.3>A (240), L1.2>A (241), G1>A (243) (237-346), CH3 E12 (362), M14 (364) (347-451), CHS K2>del (452), fused 8-mer RPQGFGPP (453-460)) (124-460)], (226-214')-disulfide with L-kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-39*01 (87.4%) -IGKJ2*02 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153'), V101 (191') (108'-214')]; dimer (232-232'':235-235'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, glycoform alfa

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