Мурлентамаб

Rec. INN (наименование, зарегистрированное ВОЗ)

immunoglobulin G1-kappa, anti-[Homo sapiens AMHR2 (anti-Müllerian hormone (AMH) receptor type 2, Müllerian inhibiting substance type II receptor, MISRII, MISR2)], humanized monoclonal antibody;
gamma1 heavy chain (1-445) [humanized VH (Homo sapiens IGHV1-3*01 (90.8%) -(IGHD)-IGHJ4*01 (92.9%)) [8.8.8] (1-115) -Homo sapiens IGHG1*01, G1m17,1 (CH1 K120 (212) (116-213), hinge (214-228), CH2 (229-338), CH3 D12 (354), M14 (356) (339-443), CHS (444-445)) (116-445)], (218-213')-disulfide with kappa light chain (1'-213') [humanized V-KAPPA (Homo sapiens IGKV1- 5*01 (86.2%) -IGKJ4*01 (100%)) [5.3.9] (1'-106') -Homo sapiens IGKC*01, Km3 A45.1 (153), V101 (191)(107'- 213')]; dimer (224-224":227-227")-bisdisulfide

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