Надекнемаб
NadecnemabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
Drugbank
DB16677
CAS
2377679-19-9
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens GFRA3 (glial cell derived neurotrophic factor family receptor alpha 3, GFRa-3)], Homo sapiens monoclonal antibody;
gamma4 heavy chain Homo sapiens (1-451) [VH (Homo sapiens IGHV3-23*04 (95.9%) -(IGHD) -IGHJ6*01 (94.4%)) CDR-IMGT [8.8.17] (26-33.51-58.97-113) (1-124) -Homo sapiens IGHG4*01 (100%), G4v5 h P10 (CH1 (125-222), hinge 1-12 S10>P (232) (223-234), CH2 (235-344), CH3 (345-449), CHS (450-451)) (125-451)], (138-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-12*01 (98.9%) -IGKJ3*01 (91.7%)) CDR-IMGT [6.3.9] (27-32.50-52.89-97) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (230-230'':233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma4 heavy chain Homo sapiens (1-451) [VH (Homo sapiens IGHV3-23*04 (95.9%) -(IGHD) -IGHJ6*01 (94.4%)) CDR-IMGT [8.8.17] (26-33.51-58.97-113) (1-124) -Homo sapiens IGHG4*01 (100%), G4v5 h P10 (CH1 (125-222), hinge 1-12 S10>P (232) (223-234), CH2 (235-344), CH3 (345-449), CHS (450-451)) (125-451)], (138-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-12*01 (98.9%) -IGKJ3*01 (91.7%)) CDR-IMGT [6.3.9] (27-32.50-52.89-97) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (230-230'':233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Nadecnemabum (латинское)
- Nadecnemab (английское)
- Nadecnemab (немецкое)
- Nadecnémab (французское)
- Nadecnemab (испанское)
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