Накситамаб

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

384585393

DB15965

1879925-92-4

immunoglobulin G1-kappa, anti-[Homo sapiens ganglioside GD2 (disialoganglioside GD2)], monoclonal antibody;
gamma1 heavy chain (1-449) [VH (Mus musculus IGHV2-9*02 (79.2%) -(IGHD) -IGHJ3*01 (91.7%)/Homo sapiens IGHV3-33*01 (72.2%) -(IGHD) -IGHJ4*01 (92.9%)) [8.7.13] (1-119) -Homo sapiens IGHG1*08p, G1m3,1 (CH1 R120 (216) (120-217), hinge (218-232), CH2 (233-342), CH3 D12 (358), L14 (360) (343-447), CHS (448-449)) (120-449)], (222- 211')-disulfide with kappa light chain (1'-211') [VKAPPA (Mus musculus IGKV6-32*02 (84.9%) - IGKJ2*03 (90.0%)/Homo sapiens IGKV3-15*01 (78.7%) -IGKJ2*03 (100%)) [6.3.6] (1'-104') -Homo sapiens IGKC*01 (100%) Km3 A45.1 (150), V101 (188) (105'-211')]; dimer (228-228":231-231")- bisdisulfide

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