Нарлумосбарт
NarlumosbartМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2646587-68-8
Химическое название
immunoglobulin G4-kappa, anti-[TNFSF11 (tumor necrosis factor (TNF) superfamily member 11, osteoclast differentiation factor, ODF, OPGL, RANKL, TRANCE, CD254)], Homo sapiens monoclonal antibody;
gamma4 heavy chain Homo sapiens (1-449) [VH (Homo sapiens IGHV3-23*01 (98.0%) -(IGHD) -IGHJ5*02 (93.8%), CDR-IMGT [8.8.15] (26-33.51-58.97-111)) (1-122) -Homo sapiens IGHG4*01, G4v5 h P10, nG4m(a) CH2 L92 (CH1 (123-220), hinge 1-12, S10>P (230) (221-232), CH2 L92 (311) (233-342), CH3 (343-447), CHS (448-449)) (123-449)], (136-215')-disulfide with kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV3-20*01 (85.8%) -IGKJ1*01 (100%), CDR-IMGT [7.3.9] (27-33.51-53.90-98)) (1'-108') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (154), V101 (192) (109'-215')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-S, glycoform alfa
gamma4 heavy chain Homo sapiens (1-449) [VH (Homo sapiens IGHV3-23*01 (98.0%) -(IGHD) -IGHJ5*02 (93.8%), CDR-IMGT [8.8.15] (26-33.51-58.97-111)) (1-122) -Homo sapiens IGHG4*01, G4v5 h P10, nG4m(a) CH2 L92 (CH1 (123-220), hinge 1-12, S10>P (230) (221-232), CH2 L92 (311) (233-342), CH3 (343-447), CHS (448-449)) (123-449)], (136-215')-disulfide with kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV3-20*01 (85.8%) -IGKJ1*01 (100%), CDR-IMGT [7.3.9] (27-33.51-53.90-98)) (1'-108') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (154), V101 (192) (109'-215')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-S, glycoform alfa
Структура
Иностранные названия
- Narlumosbartum (латинское)
- Narlumosbart (английское)
- Narlumosbart (немецкое)
- Narlumosbart (французское)
- Narlumosbart (испанское)
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