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Rec. INN (наименование, зарегистрированное ВОЗ)

2360418-68-2

immunoglobulin G4-kappa, anti-[Homo sapiens LAG3 (lymphocyte activating 3, lymphocyte-activation 3, CD223)], Homo sapiens monoclonal antibody;
gamma4 heavy chain Homo sapiens (1-446) [VH (Homo sapiens IGHV4-39*01 (96.0%) -(IGHD) -IGHJ3*02 (100%), CDR-IMGT [10.7.12] (26-35.53-59.98-109)) (1-120) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10, G4v4 CH2 A1.3, A1.2 (CH1 (121-218), hinge 1-12 S10>P (228) (219-230), CH2 F1.3>A (234), L1.2>A (235), L92 (309) (231-340), CH3 (341-445), CHS K2>del (446)) (121-446)], (134-215')-disulfide with kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV1-33*01 (96.8%) -IGKJ4*01 (100%), CDR-IMGT [6.3.10] (27'-32'.50'-52'.89'-98')) (1'-108') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (154'), V101 (192') (109'-215')]; dimer (226-226'':229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO)-K1SV cell line lacking the glutamine synthetase gene (GS-KO), glycoform alfa

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