Нелмастобарт

Rec. INN (наименование, зарегистрированное ВОЗ)

485664047

2669823-48-5

immunoglobulin G4-kappa, anti-[Homo sapiens BTN1A1 (butyrophilin subfamily 1 member A1)], humanized monoclonal antibody;
gamma4 heavy chain humanized (1-452) [VH (Homo sapiens IGHV1-46*01 (84.7%) -(IGHD) -IGHJ3*01 (92.9%) M123>T (120), CDR-IMGT [8.8.18] (26-33.51-58.97-114)) (1-125) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (126-223), hinge 1-12 S10>P (233) (224-235), CH2 L92 (314) (236-345), CH3 (346-450), CHS (451-452)) (126-452)], (139-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-33*01 (85.3%) -IGKJ2*01 (90.9%) K123>E (103'), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153'), V101 (191') (108'-214')]; dimer (231-231'':234-234'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-derived cell line lacking the glutamine synthetase (GS-KO) gene, glycoform alfa

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