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Rec. INN (наименование, зарегистрированное ВОЗ)

2640224-48-0

immunoglobulin G1-kappa, anti-[severe acute respiratory syndrome (human) coronavirus 2 (SARS- CoV-2) spike (S) glycoprotein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV3-11*01 (96.9%) -(IGHD) - IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1, G1v14 CH2 A1.3, A1.2, G1v24 CH3 L107, S114 (CH1 R120>K (217) (121- 218), hinge 1-15 (219-233), CH2 L1.3>A (237), L1.2>A (238), P114>G (332) (234-343), CH3 E12 (359), M14 (361), M107>L (431), N114>S (437) (344-448), CHS (449-450)) (121-450)], (223-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-33*01 (96.8%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (229-229'':232-232'')- bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV lacking the glutamine synthetase (GS-KO) gene, glycoform alfa

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