Нолаветбарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2750248-93-0

immunoglobulin G2-kappa, anti-[Canis lupus familiaris IL31RA (interleukin 31 receptor A)], caninized monoclonal antibody;
gamma2 heavy chain caninized (1-453) [VH (Canis lupus familiaris IGHV4-1*01 (77.8%) -(IGHD) -IGHJ4*01 (86.7%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Canis lupus familiaris IGHG2*02, G2v2 CH2 A1.3, A1.2, G114 (CH1 (120-216), hinge 1-19 (217-235), CH2 M1.3>A (239), L1.2>A (240), P114>G (334) (236-345), CH3 (346-452), CHS K2>del (453)) (120-453)], (134-213')-disulfide with kappa light chain caninized (1'-213') [V-KAPPA (Canis lupus familiaris IGKV4-15*01 (76.0%) -IGKJ3*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Canis lupus familiaris IGKC*01 (100%) (108'-213')]; dimer (231-231'':234-234'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa

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