Обекселимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

DB15032

1690307-05-1

immunoglobulin G1-kappa, anti-[Homo sapiens CD19 (B lymphocyte surface antigen B4, Leu-12)], monoclonal antibody;
gamma1 heavy chain (1-451) [VH (Mus musculus IGHV1- 14*01 (77.6%)/Homo sapiens IGHV1-3*01 (73.5%) - (IGHD)-Homo sapiens IGHJ4*01 (100%)) [8.8.14] (1-121) - Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 (CH1 R120>K (218) (122-219), hinge (220-234), CH2 S29>E (271), L113>F (332) (235-344), CH3 E12 (360), M14 (362) (345-449), CHS (450-451)) (122-451)], (224-219')-disulfide with kappa light chain (1'-219') [V-KAPPA (Mus musculus IGKV2-137*01 (75.0%)/Homo sapiens IGKV3D-11*03 (73.7%) -Homo sapiens IGKJ2*01 (90.9%)) [11.3.9] (1'- 112') -Homo sapiens IGKC*01, Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (230-230":233-233")-bisdisulfide

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