Оциперлимаб
OciperlimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2342597-93-5
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens TIGIT (T-cell immunoreceptor with Ig domain and ITIM, V-set Ig member 9, VSIG9, V-set and transmembrane member 3, VSTM3)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV3-66*01 (88.8%) -(IGHD) -IGHJ4*01 (100%)) CDR-IMGT [8.8.12] (26-33.51-58.97-108) (1-119) -Homo sapiens IGHG1*01 nG1m1, G1m17 (CH1 K120 (216) (120-217), hinge 1-15 (218-232), CH2 (233-342), CH3 E12 (358), M14 (360) (343-447), CHS (448-449)) (120-449)], (222-214')-disulfide with kappa light chain humanized (1’-214’) [V-KAPPA (Homo sapiens IGKV3-15*01 (87.4%) -IGKJ4*01 (100%)) CDR-IMGT [6.3.9] (27-32.50-52.89-97) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1 (153), V101 (191) (108'-214')];
dimer (228-228":231-231")-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma1 heavy chain humanized (1-449) [VH (Homo sapiens IGHV3-66*01 (88.8%) -(IGHD) -IGHJ4*01 (100%)) CDR-IMGT [8.8.12] (26-33.51-58.97-108) (1-119) -Homo sapiens IGHG1*01 nG1m1, G1m17 (CH1 K120 (216) (120-217), hinge 1-15 (218-232), CH2 (233-342), CH3 E12 (358), M14 (360) (343-447), CHS (448-449)) (120-449)], (222-214')-disulfide with kappa light chain humanized (1’-214’) [V-KAPPA (Homo sapiens IGKV3-15*01 (87.4%) -IGKJ4*01 (100%)) CDR-IMGT [6.3.9] (27-32.50-52.89-97) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1 (153), V101 (191) (108'-214')];
dimer (228-228":231-231")-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Ociperlimabum (латинское)
- Ociperlimab (английское)
- Ociperlimab (немецкое)
- Ociperlimab (французское)
- Ociperlimab (испанское)
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