Огалвибарт
OgalvibartМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
PubChem
461453495
CAS
2599039-60-6
Химическое название
immunoglobulin G1-kappa, anti-[severe acute respiratory syndrome (human) coronavirus 2 (SARS- CoV-2) spike (S) glycoprotein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV3-30*01 (95.9%) -(IGHD) - IGHJ4*01 (100%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v24 CH3 L107, S114 (CH1 R120 (216) (120-217), hinge 1-15 (218-232), CH2 (233-342), CH3 E12 (360), M14 (362), M107>L (430), N114>S (436) (343-447), CHS K2>del (448)) (120-448)], (222-214')- disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-5*01 (96.8%) - IGKJ1*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (228- 228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma1 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV3-30*01 (95.9%) -(IGHD) - IGHJ4*01 (100%), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v24 CH3 L107, S114 (CH1 R120 (216) (120-217), hinge 1-15 (218-232), CH2 (233-342), CH3 E12 (360), M14 (362), M107>L (430), N114>S (436) (343-447), CHS K2>del (448)) (120-448)], (222-214')- disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-5*01 (96.8%) - IGKJ1*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (228- 228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Ogalvibartum (латинское)
- Ogalvibart (английское)
- Ogalvibart (немецкое)
- Ogalvibart (французское)
- Ogalvibart (испанское)
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