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Rec. INN (наименование, зарегистрированное ВОЗ)

2851870-28-3

immunoglobulin G1-kappa, anti-[Homo sapiens KAAG1 (kidney associated DCDC2 antisense RNA 1, kidney associated antigen 1, RU2AS, RU2 antisense gene protein)], humanized and chimeric monoclonal antibody;
H-gamma1 heavy chain humanized (1-445) [VH (Homo sapiens IGHV1-46*01 (80.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG1*01 (100%), G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (213) (117-214), hinge 1-15 (215-229), CH2 (230-339), CH3 D12 (355), L14 (357) (340-444), CHS K2>del (445)) (117-445)], (219-219')-disulfide with L-kappa light chain chimeric (1'-219') [V-KAPPA Musmus/Homsap (Mus musculus IGKV1-117*01 (89.0%) -IGKJ2*03 (90.9%) S120>Q (105)/Homo sapiens IGKV2-29*02 (89.0%) -IGKJ2*01 (100%), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158'), V101 (196') (113'-219')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa

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