Олоктинебарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2669063-84-5

immunoglobulin G4-kappa, anti-[Homo sapiens LGALS3 (galectin 3)], humanized monoclonal antibody;
gamma4 heavy chain humanized (1-442) [VH (Homo sapiens IGHV1-3*01 (88.7%) -(IGHD) -IGHJ6*01 (93.3%), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (117-214), hinge 1-12 S10>P (224) (215-226), CH2  L92 (305) (227-336), CH3 (337-441), CHS K2>del (442)) (117-442)], (130-219')-disulfide with kappa light chain humanized (1'-219') [V-KAPPA (Homo sapiens IGKV2D-29*02 (89.0%) -IGKJ2*01 (100%), CDR-IMGT [11.3.9] (27-37.55-57.94-102)) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (222-222'':225-225'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

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