Омопрубарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2763342-87-4

immunoglobulin G2/G4-kappa, anti-[Homo sapiens C5 (complement 5)], monoclonal antibody;
gamma2/gamma4 heavy chain (1-448) [VH (Homo sapiens IGHV1-2*06 (85.7%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [8.8.15] (26-33.51-58.97-111)) (1-122) -Homo sapiens IGHG2*01 CH1-hinge (CH1 (123-220), hinge 1-15 (221-232)) -Homo sapiens IGHG4*01 CH2-CH3, nG4m(a) CH2 L92, G4v7 CH2 delE1.4, P1.3, V1.2, A1.1, G4v21 CH2 Y15.1, T16, E18 (CH2 L92 (310) E1.4>del, F1.3>P (235), L1.2>V (236), G1.1>A (237), M>Y15.1 (253), S>T16 (255), T>E18 (257) (233-341), CH3 (342-446), CHS (447-448)) (123-448)], (136-214')-disulfide with kappa light chain (1'-214') [V-KAPPA (Homo sapiens IGKV1-39*01 (77.9%) -IGKJ3*01 (81.8%) P120>G (100'), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (153'), V101 (191') (108'-214')]; dimer (224-224'':225-225'':228-228'':231-231'')-tetrakisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa

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