Опелкибарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2771389-44-5

immunoglobulin G1-kappa, anti-[Homo sapiens KIT (KIT proto-oncogene receptor tyrosine kinase, c-kit, SCFR, CD117)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-453) [VH (Homo sapiens IGHV5-51*01 (94.9%) -(IGHD) -IGHJ3*02 (93.3%) M123>L (118), CDR-IMGT [8.8.16] (26-33.51-58.97-112)) (1-123) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, G1v14 CH2 A1.3, A1.2, G1v76 CH2 C27, G1v77 CH3 A115 (CH1 K120 (220) (124-221), hinge 1-15 (222-236), CH2 L1.3>A (240), L1.2>A (241), D27>C (271) (237-346), CH3 D12 (362), L14 (364) H115>A (441) (347-451), CHS (452-453)) (124-453)], (226-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-12*01 (89.5%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (153'), V101 (191') (108'-214')]; dimer (232-232'':235-235'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-DG44, glycoform alfa

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