Ориланолимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

DB15312

2066544-85-0

immunoglobulin G4-kappa, anti-[Homo sapiens FCGRT (Fc fragment of IgG receptor and transporter, neonatal Fc receptor, FcRn, transmembrane alpha chain of the neonatal receptor)], monoclonal antibody;
gamma4 heavy chain (1-444) [VH (Mus musculus IGHV1- 81*01 (92.9%)/Homo sapiens IGHV1-18*01 (77.6%) - (IGHD) -Homo sapiens IGHJ3*02 (83.3%)) [8.8.11] (1-118) -Homo sapiens IGHG4*01 (CH1 (119-216), hinge S10>P (226) (217-228), CH2 (229-338), CH3 (339-443), CHS K2>del (444)) (119-444)], (132-214')-disulfide with kappa light chain (1'-214') [V-KAPPA (Mus musculus IGKV13- 85*01 (88.4%)/Homo sapiens IGKV1-NL1*01 (83.2%) - Homo sapiens IGKJ4*01 (100%)) [6.3.9] (1'-107') -Homo sapiens IGKC*01, Km3 A45.1 (153), V101 (191)(108'- 214')]; dimer (224-224'':227-227'')-bisdisulfide

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