Пацибекитуг

Prop. INN (наименование, предложенное ВОЗ)

2948444-06-0

immunoglobulin G2-kappa, anti-[Homo sapiens IL6 (interleukin 6, IL-6)], Homo sapiens monoclonal antibody;
H-gamma2 heavy chain Homo sapiens (1-442) [VH (Homo sapiens IGHV4-34*12 (95.9%) -(IGHD) -IGHJ3*02 (93.8%), CDR-IMGT [8.7.10] (26-33.51-57.96-105)) (1-116) -Homo sapiens IGHG2*01 (100%), G2m.. CH2 V45.1 (CH1 (117-214), hinge 1-12 (215-226), CH2 V45.1 (277) (227-335), CH3 (336-440), CHS (441-442)) (117-442)], (130-214')-disulfide with L-kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1D-16*01 (98.9%) -IGKJ1*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153'), V101 (191') (108'-214')]; dimer (218-218'':219-219'':222-222'':225-225'')-tetrakisdisulfide, produced in Chinese hamster ovary (CHO)-K1SV cell line, lacking the glutamine synthetase gene (GS-KO), glycoform alfa

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