Патидистроген бексопарвовец

Rec. INN (наименование, зарегистрированное ВОЗ)

2376210-48-7

recombinant self-complementary (dimeric) non- replicating adeno-associated virus serotype rh.74 (AAVrh74) vector encoding codon-optimized human alpha-sarcoglycan (hSGCA), under the control of a triple E box muscle creatine kinase (tMCK) promoter/enhancer, followed by a chimeric intron,) composed of the 5' donor site from the human beta- globin gene and the branchpoint and 3' splice acceptor site from the IgG heavy chain variable region, and terminated by a small synthetic polyadenylation (polyA) signal sequence, flanked by adeno-associated virus 2 (AAV2) inverted terminal repeats (ITRs).

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