Пэгфосимер марганца

Rec. INN (наименование, зарегистрированное ВОЗ)

2641234-28-6

polymer nanoparticles synthesized from tetramethyl P,P'-[1,7- bis(triethoxysilyl)heptane-4,4-diyl]bisphosphonate (~52 molecules per particle on average) by
(i) hydrolysis of the triethoxysilyl groups and ~75% of the dimethyl phosphonate groups and condensation of the resulting bis-silanetriol to a polymeric network with Si-O-Si linkages,
(ii) coating of the core particles by hydrolysis of α-({3,5-bis[3-(triethoxysilyl)propoxy]phenyl}methyl)-ω-methoxypoly(oxyethylene) (~18 molecules per particle on average) and condensation of the resulting silanetriol groups with surficial silanol groups, and (iii) addition of a manganese(2+) salt to form hydrated polymeric ammonium manganese(2+) sodium (≈ 29:13:65) phosphonate complexes

C₁₂₄₄H₂₆₈₆Mn₁₃N₂₉Na₆₅O₉₈₅P₁₀₄Si₁₄₀

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