Пегсебренатид

Rec. INN (наименование, зарегистрированное ВОЗ)

2243292-26-2

exendin-4-oyl-L-cysteinamide, conjugated at Cys40 via a 1-O-(3-{O'-[3-(3-maleimidopropanamido) propyl]polyethylene glycol-O-yl} propylaminocarbonyl)glycerol linker with two O-methylpoly(ethylene glycol) chains:
L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl- L-seryl-L-α-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-α-glutamyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-α-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-L-seryl-S-{(3RS)-1-[3-({3-[α-{3-[({(2RS)-2,3-bis[α-methylpoly(oxyethylene)-ω-oxy]propoxy}carbonyl)amino]propyl}poly(oxyethylene)-ω-oxy]propyl}amino)-3-oxopropyl]-2,5-dioxopyrrolidin-3-yl}-L-cysteinamide

C₂₀₆H₃₁₈N₅₄O₆₉S₂(C₂H₄O)_m+2n; m≈10; n≈20

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