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Rec. INN (наименование, зарегистрированное ВОЗ)

2649372-23-4

human cystathionine γ-lyase (CGL, cysteine-protein sulfhydrase, γ-cystathionase, CTH, EC:4.4.1.1) variant (E⁵⁹>I, S⁶³>L, L⁹¹>M, R¹¹⁹>D, K²⁶⁸>R, T³¹¹>G, E³³⁹>V, I³⁵³>S), conjugated at N² of M¹ and at the N⁶ of K⁴, K⁷³, K¹⁴¹, K¹⁷⁸, K²⁸⁸, K³³⁰ with [α-methylpoly(oxyethylene)-ω- oxy]acetyl groups (~50% or >50% at each site, about 120 oxyethylene units per chain on average) (~50% or >50% per site, about 120 oxyethylene units per chain on average), tetramer, produced in Escherichia coli; [E⁵⁹>I, S⁶³>L, L⁹¹>M, R¹¹⁹>D, K²⁶⁸>R, T³¹¹>G, E³³⁹>V, I³⁵³>S]-human cystathionine γ-lyase (CGL, cysteine- protein sulfhydrase, γ-cystathionase, CTH, EC:4.4.1.1), non-covalent homotetramer, substituted at N² of Met 1 and N⁶ of Lys 4, 73, 141, 178, 288, and 330 with [α-methylpoly(oxyethylene)-ω-oxy]acetyl groups (~50% or >50% at each site, about 120 oxyethylene units per chain on average), produced in Escherichia coli

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