Пиканкибарт

Rec. INN (наименование, зарегистрированное ВОЗ)

2622900-74-5

immunoglobulin G1-kappa, anti-[Homo sapiens IL23A (interleukin 23 subunit alpha; IL-23A, IL-23 subunit p19, IL23p19)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-444) [VH (Homo sapiens IGHV1-2*02 (93.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.8] (27-32.51-58.97-104)) (1-115) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, G1v21 CH2 Y15.1, T16, E18 (CH1 K120 (212) (116-213), hinge 1-15 (214-228), CH2 M15.1>Y (250), S16>T (252), T18>E (254) (229-338), CH3 D12 (354), L14 (356) (339-443), CHS K2>del (444)) (116-444)], (218-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-39*01 (88.4%) -IGKJ2*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (153), V101 (191) (108'-214')]; dimer (224-224'':227-227'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV lacking the glutamine synthetase (GS-KO) gene, glycoform alfa

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