Пимивалимаб
PimivalimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2293951-22-9
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens PDCD1 (programmed cell death 1, PD-1, PD1, CD279)], Homo sapiens monoclonal antibody;
gamma4 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV1-46*01 (96.9%) -(IGHD) -IGHJ5*02 (100%)) CDR-IMGT [8.8.11] (26-33.51-58.97-107) (1-118) -Homo sapiens IGHG4*01 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-5*01 (97.9%) -IGKJ4*01 (100%)) CDR-IMGT [6.3.9] (27-32.50-52.89-97) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108’-214’)];
dimer (224-224":227-227")-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma4 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV1-46*01 (96.9%) -(IGHD) -IGHJ5*02 (100%)) CDR-IMGT [8.8.11] (26-33.51-58.97-107) (1-118) -Homo sapiens IGHG4*01 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-5*01 (97.9%) -IGKJ4*01 (100%)) CDR-IMGT [6.3.9] (27-32.50-52.89-97) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108’-214’)];
dimer (224-224":227-227")-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Pimivalimabum (латинское)
- Pimivalimab (английское)
- Pimivalimab (немецкое)
- Pimivalimab (французское)
- Pimivalimab (испанское)
Подробнее по теме
Узнайте дополнительные сведения о действующем веществе Пимивалимаб: