Плозасиран

Prop. INN (наименование, предложенное ВОЗ)

2379776-40-4

all-P-ambo-3′-O-[({(1s,4s)-4-[(3S,8S)-17-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]-3,8-bis[(2-{2-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]ethoxy}ethyl)carbamoyl]-6,11-dioxo-15-oxa-2,7,12-triazaheptadecan-1-oyl]cyclohexyl}oxy)(sulfanyl)phosphoryl]-1'-de(6-amino-9H-purin-9-yl)-2'-deoxy-P-thioadenylyl-(5'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-deoxy-2'-fluoroguanylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-deoxy-2'-fluoroadenylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methylinosinylyl-(3'→5')-2'-O-methyl-P-thioadenylyl-(3'→3')-1'-de(6-amino-9H-purin-9-yl)-2'-deoxyadenosine duplex with all-P-ambo-2'-O-methyl-P-thiouridylyl-(5'→3')-2'-deoxy-2'-fluoroguanylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-O-methylcytidylyl-(5'→3')-2'-deoxy-2'-fluorouridylyl-2'-O-methylguanylyl-(5'→3')-2'-deoxy-2'-fluorouridylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluoroguanylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-deoxy-2'-fluoro-P-thiocytidylyl-(5'→3')-2'-O-methyl-P-thioadenylyl-(5'→3')-2'-deoxy-2'-fluoro-P-thiocytidylyl-(5'→3')-2'-O-methyluridine

C₄₉₃H₆₅₄F₁₁N₁₆₄O₃₁₁P₄₃S₇

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