Плутавимаб

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

2529854-88-2

immunoglobulin G1-kappa, anti-[severe acute respiratory syndrome (human) coronavirus 2 (SARS- CoV-2) spike (S) glycoprotein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV3-53*01 (95.9%) -(IGHD) - IGHJ6*01 (100%), CDR-IMGT [8.7.11] (26-33.51-57.96-106)) (1-117) -Homo sapiens IGHG1*03 (100%), G1m3, nG1m1, G1v14 CH2 A1.3, A1.2(CH1 R120 (214) (118-215), hinge 1-15 (216-230), CH2 L1.3>A (234), L1.2>A (235) (231-340), CH3 E12 (356), M14 (358) (341-445), CHS (446-447)) (118-447)], (220-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-12*01 (93.7%) -IGKJ2*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153),V101 (191) (108'-214')]; dimer (226-226'':229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa

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