Ползастобарт
PolzastobartМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2640981-19-5
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens LILRB2 (leukocyte immunoglobulin like receptor B2, ILT4, LIR-2, MIR10, CD85d)], humanized monoclonal antibody;
gamma4 heavy chain humanized (1-450) [VH humanized (Homo sapiens IGHV2-5*01 (86,9%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [10.7.15] (26-35.53-59.98-112)) (1-123) -Homo sapiens IGHG4*01, IGHG4v5 h P10, nG4m(a) CH2 L92 (CH1 (124-221), hinge 1-12 S10>P (231) (222-233), CH2 L92 (312) (234-343), CH3 (344-448), CHS (449-450)) (124-450)], (137-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA Homo sapiens IGKV1-33*01 (83.2%) -IGKJ2*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (229-229'':232-232'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma4 heavy chain humanized (1-450) [VH humanized (Homo sapiens IGHV2-5*01 (86,9%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [10.7.15] (26-35.53-59.98-112)) (1-123) -Homo sapiens IGHG4*01, IGHG4v5 h P10, nG4m(a) CH2 L92 (CH1 (124-221), hinge 1-12 S10>P (231) (222-233), CH2 L92 (312) (234-343), CH3 (344-448), CHS (449-450)) (124-450)], (137-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA Homo sapiens IGKV1-33*01 (83.2%) -IGKJ2*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (229-229'':232-232'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Polzastobartum (латинское)
- Polzastobart (английское)
- Polzastobart (немецкое)
- Polzastobart (французское)
- Polzastobart (испанское)
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