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Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

2368950-15-4

immunoglobulin G1-kappa, anti-[Homo sapiens GDF15 (growth differentiation factor 15, PLAB, MIC-1, PDF, MIC1, NAG-1, PTGFB)], monoclonal antibody;
gamma1 heavy chain (1-449) [VH (Homo sapiens IGHV1-69*01 (93.9%) -(IGHD) -IGHJ1*01 (100%)) CDR-IMGT [8.8.13] (26-33.51-58.97-109) (1-120) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1, G1v14 CH2 A1.3, A1.2 (CH1 R120>K (217) (121-218), hinge 1-15 (219-233), CH2 L1.3>A (237), L1.2>A (238), G1>A (240) (234-343), CH3 E12 (359), M14 (361) (344-448), CHS K>del (449)) (121-449)], (223-214')-disulfide with kappa light chain (1'-214') [V-KAPPA (Homo sapiens IGKV3-11*01 (91.6%) -IGKJ1*01 (100%)) CDR-IMGT [6.3.9] (27-32.50-52.89-97) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (229-229'':232-232'')-bisdisulfide, produced in Chinese hamster ovary (CHO)-K1SV cell line lacking the glutamine synthetase gene (GSKO), glycoform alfa

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