Прафносбарт
PrafnosbartМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2566473-71-8
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens ACVR1 (activin A receptor type 1, ACVRLK2, ALK2, ACVR1A, SKR1)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-451) [VH humanized (Homo sapiens IGHV3-21*01 (88.7%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v14 CH2 A1.3, A1.2 (CH1 R120 (218) (122-219), hinge 1-15 (220-234), CH2 L1.3>A (238), L1.2>A (239) (235-344), CH3 E12 (360), M14 (362) (345-449), CHS (450-451)) (122-451)], (224-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV3-20*01 (81.2%) -IGKJ2*01 (91.7%), CDR-IMGT [5.3.10] (27-31.49-51.88-97)) (1'-107') -Homo sapiens IGKC*01, Km3, T1.3>A (109), A45.1 (153), V101 (191) (108'-214')]; dimer (230-230'':233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-S, glycoform alfa
gamma1 heavy chain humanized (1-451) [VH humanized (Homo sapiens IGHV3-21*01 (88.7%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [8.8.14] (26-33.51-58.97-110)) (1-121) -Homo sapiens IGHG1*03, G1m3, nG1m1, G1v14 CH2 A1.3, A1.2 (CH1 R120 (218) (122-219), hinge 1-15 (220-234), CH2 L1.3>A (238), L1.2>A (239) (235-344), CH3 E12 (360), M14 (362) (345-449), CHS (450-451)) (122-451)], (224-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV3-20*01 (81.2%) -IGKJ2*01 (91.7%), CDR-IMGT [5.3.10] (27-31.49-51.88-97)) (1'-107') -Homo sapiens IGKC*01, Km3, T1.3>A (109), A45.1 (153), V101 (191) (108'-214')]; dimer (230-230'':233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-S, glycoform alfa
Структура
Иностранные названия
- Prafnosbartum (латинское)
- Prafnosbart (английское)
- Prafnosbart (немецкое)
- Prafnosbart (французское)
- Prafnosbart (испанское)
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