Продувофусп

Prop. INN (наименование, предложенное ВОЗ)

2925698-93-5

human complement factor H (H factor 1, CFH) catalytic domain containing fragment (1-305) fused to a humanized heavy chain variable domain only (VHH) immunoglobulin with the CDRs originating from Lama glama (306-434) [Homo sapiens IGHV3-23*04 -(IGHD) - IGHJ4*01, CDR-Kabat [5.17.20] (336-340.355-371.404-423)] fused via peptide linker ⁴³⁵GGGGA⁴³⁹ to the ⁴⁴⁰CRGDRGDRGDRGDC⁴⁵³ peptide containing four RGD (human integrin recognition motif repeats (441- 452)) arranged as a cyclic polypeptide (C⁴⁴⁰ disulfide-bridged to C⁴⁵³), produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV

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