Пулоцимаб
PulocimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2428381-49-9
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens KDR (kinase insert domain receptor, vascular endothelial growth factor receptor 2, VEGFR2, VEGF-R2, FLK1, CD309)], monoclonal antibody;
gamma1 heavy chain (1-446) [VH (Homo sapiens IGHV3-21*01 (99.0%) -(IGHD) -IGHJ3*02 (100%), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (213) (117-214), hinge 1-15 (215-229), CH2 (230-339), CH3 D12 (355), L14 (357) (340-444), CHS (445-446)) (117-446)], (219-214')-disulfide with kappa light chain (1'-214') [V-KAPPA (Homo sapiens IGKV1-12*01 (84.2%) -IGKJ4*01 (90.9%) E125>D (105), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma1 heavy chain (1-446) [VH (Homo sapiens IGHV3-21*01 (99.0%) -(IGHD) -IGHJ3*02 (100%), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (213) (117-214), hinge 1-15 (215-229), CH2 (230-339), CH3 D12 (355), L14 (357) (340-444), CHS (445-446)) (117-446)], (219-214')-disulfide with kappa light chain (1'-214') [V-KAPPA (Homo sapiens IGKV1-12*01 (84.2%) -IGKJ4*01 (90.9%) E125>D (105), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Pulocimabum (латинское)
- Pulocimab (английское)
- Pulocimab (немецкое)
- Pulocimab (французское)
- Pulocimab (испанское)
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