Квизовалимаб
QuisovalimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2427667-03-4
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens TNFSF14 (tumor necrosis factor (TNF) superfamily member 14, LIGHT, HVEM-L, CD258)], Homo sapiens monoclonal antibody;
gamma4 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV4-34*01 (95.9%) -(IGHD) -IGHJ6*01 (100%), CDR-IMGT [8.7.16] (26-33.51-57.96-111)) (1-122) -Homo sapiens IGHG4*01, G4v5 h P10, G4v3 CH2 E1.2 (CH1 (123-220), hinge 1-12 S10>P (230) (221-232), CH2 L1.2>E (237) (233-342), CH3 (343-447), CHS K>del (448)) (123-448)], (136-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-13*02 (97.9%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (228-228'':231-231'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-K1SV cell line, glycoform alfa
gamma4 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV4-34*01 (95.9%) -(IGHD) -IGHJ6*01 (100%), CDR-IMGT [8.7.16] (26-33.51-57.96-111)) (1-122) -Homo sapiens IGHG4*01, G4v5 h P10, G4v3 CH2 E1.2 (CH1 (123-220), hinge 1-12 S10>P (230) (221-232), CH2 L1.2>E (237) (233-342), CH3 (343-447), CHS K>del (448)) (123-448)], (136-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-13*02 (97.9%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (228-228'':231-231'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-K1SV cell line, glycoform alfa
Структура
Иностранные названия
- Quisovalimabum (латинское)
- Quisovalimab (английское)
- Quisovalimab (немецкое)
- Quisovalimab (французское)
- Quisovalimab (испанское)
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