Ралзапастотуг
RalzapastotugМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2581724-89-0
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens TIGIT (T-cell immunoreceptor with Ig domain and ITIM, V-set Ig member 9, VSIG9, V-set and transmembrane member 3, VSTM3)], humanized monoclonal antibody;
gamma1 heavy chain humanized (1-451) [VH (Homo sapiens IGHV4-4*10 (90.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [9.7.14] (26-34.52-58.97-110)) (1-121) -Homo sapiens IGHG1*01, G1m17,1 (CH1 K120 (218) (122-219), hinge 1-15 (220-234), CH2 (235-344), CH3 D12 (360), L14 (362) (345-449), CHS (450-451)) (122-451)], (224-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV3-15*01 (86.5%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (230-230'': 233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
gamma1 heavy chain humanized (1-451) [VH (Homo sapiens IGHV4-4*10 (90.8%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [9.7.14] (26-34.52-58.97-110)) (1-121) -Homo sapiens IGHG1*01, G1m17,1 (CH1 K120 (218) (122-219), hinge 1-15 (220-234), CH2 (235-344), CH3 D12 (360), L14 (362) (345-449), CHS (450-451)) (122-451)], (224-214')-disulfide with kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV3-15*01 (86.5%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (230-230'': 233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Структура
Иностранные названия
- Ralzapastotugum (латинское)
- Ralzapastotug (английское)
- Ralzapastotug (немецкое)
- Ralzapastotug (французское)
- Ralzapastotug (испанское)
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