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Prop. INN (наименование, предложенное ВОЗ)

2994192-38-8

immunoglobulin G1-kappa, anti-[Homo sapiens KARS1 (lysyl-tRNA synthetase 1)], Homo sapiens monoclonal antibody;
H-gamma1 heavy chain Homo sapiens (1-446) [VH (Homo sapiens IGHV3-23*01 (92.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (213) (117-214), hinge 1-15 (215-229), CH2 (230-339), CH3 D12 (355), L14 (357) (340-444), CHS (445-446)) (117-446)], (219-217')-disulfide with V-lambda-C-kappa light chain Homo sapiens (1'-217') [V-LAMBDA (Homo sapiens IGLV1-47*02 (88.5%) -IGLJ2*01 (100%), CDR-IMGT [8.3.11] (26'-33'.51'-53'.90'-100')) (1'-110') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (156'), V101 (194')) (111'-217')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, lacking the glutamine synthetase (GS-KO) gene, glycoform alfa

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