Рецибокибарт

Prop. INN (наименование, предложенное ВОЗ)

2744274-17-5

immunoglobulin G1-kappa, anti-[Homo sapiens IL1RL2 (interleukin 1 receptor like 2, IL1 receptor-related protein 2, IL1Rrp2, IL1RRP2, IL-36 receptor, IL-36R)], humanized monoclonal antibody;
H-gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV1-2*06 (88.8%) -(IGHD) -IGHJ6*01 (90.9%) T123>L (114), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, G1v14 CH2 A1.3, A1.2 (CH1 R120 (216) (120-217), hinge 1-15 (218-232), CH2 L1.3>A (236), L1.2>A (237) (233-342), CH3 E12 (358), M14 (360) (343-447), CHS K2>del (448)) (120-448)], (222-215')-disulfide with L-kappa light chain humanized (1'-215') [V-KAPPA (Homo sapiens IGKV3-20*01 (90.6%) -IGKJ2*01 (100%), CDR-IMGT [7.3.9] (27'-33'.51'-53'.90'-98')) (1'-108') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (154'), V101 (192')) (109'-215')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

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