Ресугосбарт
ResugosbartМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2647412-09-5
Химическое название
immunoglobulin G4-kappa, anti-[Homo sapiens SOST (sclerostin)], monoclonal antibody;
gamma4 heavy chain (1-444) [VH (Homo sapiens IGHV1-18*01 (79,6%) -(IGHD) -IGHJ4*01 (93,3%), CDR-IMGT [8.8.10] (26-33.51-58.97-106)) (1-117) -Homo sapiens IGHG4*01, IGHG4v5 h P10, nG4m(a) CH2 L92 (CH1 (118-215), hinge 1-12 S10>P (225) (216-227), CH2 L92 (306) (228-337), CH3 (338-442), CHS (443-444)) (118-444)], (131-214')-disulfide with kappa light chain (1'-214') [V-KAPPA (Mus musculus IGKV6-32*01 (81.9%) -IGKJ1*01 (90,9%)/Homo sapiens IGKV1-39*01 (81.1%) -IGKJ4*01 (91,7%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (223-223'':226-226'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV lacking the glutamine synthetase (GS-KO) gene, glycoform alfa
gamma4 heavy chain (1-444) [VH (Homo sapiens IGHV1-18*01 (79,6%) -(IGHD) -IGHJ4*01 (93,3%), CDR-IMGT [8.8.10] (26-33.51-58.97-106)) (1-117) -Homo sapiens IGHG4*01, IGHG4v5 h P10, nG4m(a) CH2 L92 (CH1 (118-215), hinge 1-12 S10>P (225) (216-227), CH2 L92 (306) (228-337), CH3 (338-442), CHS (443-444)) (118-444)], (131-214')-disulfide with kappa light chain (1'-214') [V-KAPPA (Mus musculus IGKV6-32*01 (81.9%) -IGKJ1*01 (90,9%)/Homo sapiens IGKV1-39*01 (81.1%) -IGKJ4*01 (91,7%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (223-223'':226-226'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV lacking the glutamine synthetase (GS-KO) gene, glycoform alfa
Структура
Иностранные названия
- Resugosbartum (латинское)
- Resugosbart (английское)
- Resugosbart (немецкое)
- Кésugosbart (французское)
- Resugosbart (испанское)
Подробнее по теме
Узнайте дополнительные сведения о действующем веществе Ресугосбарт: