Ревакинаген тароретцел
Revakinagene taroretcelМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
Химическое название
Allogeneic human adult retinal pigment epithelial (RPE) cell line stably transfected with a plasmid encoding human ciliary neurotrophic factor (CNTF).
An allogeneic human adult retinal pigment epithelial (RPE) cell line stably transfected with a plasmid encoding human ciliary neurotrophic factor (CNTF) fused in frame to the murine immunoglobulin mu-factor VDJ4C1 signal peptide, under the control of a mouse metallothionein promoter and a human growth hormone polyadenylation signal. The plasmid also contains three eukaryotic expression cassettes for the selectable markers neomycin resistance, mouse DHFR (dihydrofolate reductase) and HSV-TK (thymidine kinase), plus the bacterial components of the pUC18 backbone, including the ampicillin resistance gene (AmpR), origin of replication (ORI) and LacZ gene (alpha fragment of β-galactosidase).
An allogeneic human adult retinal pigment epithelial (RPE) cell line stably transfected with a plasmid encoding human ciliary neurotrophic factor (CNTF) fused in frame to the murine immunoglobulin mu-factor VDJ4C1 signal peptide, under the control of a mouse metallothionein promoter and a human growth hormone polyadenylation signal. The plasmid also contains three eukaryotic expression cassettes for the selectable markers neomycin resistance, mouse DHFR (dihydrofolate reductase) and HSV-TK (thymidine kinase), plus the bacterial components of the pUC18 backbone, including the ampicillin resistance gene (AmpR), origin of replication (ORI) and LacZ gene (alpha fragment of β-galactosidase).
Структура
Иностранные названия
- Revakinagenum taroretcelum (латинское)
- Revakinagene taroretcel (английское)
- Revakinagen taroretcel (немецкое)
- Révakinagène taroretcel (французское)
- Revakinagén taroretcel (испанское)
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