Рилипрубарт

Rec. INN (наименование, зарегистрированное ВОЗ)

DB18355

2756228-76-7

immunoglobulin G4-kappa, anti-[Homo sapiens C1S (complement C1s)], monoclonal antibody;
gamma4 heavy chain (1-446) [VH Musmus/Homsap (Mus musculus IGHV14-3*02 (82.7%) -(IGHD) -IGHJ2*01 (92.9%)/Homo sapiens IGHV1-46*02 (75.5%) -(IGHD) -IGHJ4*01 (92.9%) L123>T (114)), CDR-IMGT [8.8.12] (26-33.51-58.97-108)) (1-119) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10, G4v3 CH2 E1.2, G4v24 CH3 L107, S114 (CH1 (120-217), hinge 1-12 S10>P (227) (218-229), CH2 L1.2>E (234), L92 (308) (230-339), CH3 M107>L (427), N114>S (433) (340-444), CHS (445-446)) (120-446)], (133-218')-disulfide with kappa light chain  (1'-218') [V-KAPPA Musmus/Homsap (Mus musculus IGKV3-4*01 (88.9%) -IGKJ1*01 (91.7%)/Homo sapiens IGKV4-1*01 (74.3%) -IGKJ4*01 (100%)), CDR-IMGT [10.3.9] (27-36.54-56.93-101)) (1'-111') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (157), V101 (195) (112'-218')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

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