Рилтоветбарт
RiltovetbartМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2641479-65-2
Химическое название
immunoglobulin G2-kappa, anti-[Canis lupus familiaris IL31 (interleukin 31)], caninized monoclonal antibody;
gamma2 heavy chain caninized (1-453) [VH (Canis lupus familiaris IGHV3-35*01 (89.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Canis lupus familiaris IGHG2*02, G2v2 CH3 H114 (CH1 (119-215), hinge 1-19 (216-234), CH2 (235-344), CH3 N114>H (440) (345-451), CHS (452-453)) (119-453)], (133-217')-disulfide with kappa light chain caninized (1'-217') [V-KAPPA (Canis lupus familiaris IGKV3-18*02 (85.1%) -IGKJ3*01 (91.7%), CDR-IMGT [10.3.9] (27-36.54-56.93-101)) (1'-111') -Canis lupus familiaris IGKC*01 (100%) (112'-217')]; dimer (230-230'':233-233'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-derived cell line transfected with the glutamine synthetase (GS) gene, glycoform alfa
gamma2 heavy chain caninized (1-453) [VH (Canis lupus familiaris IGHV3-35*01 (89.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Canis lupus familiaris IGHG2*02, G2v2 CH3 H114 (CH1 (119-215), hinge 1-19 (216-234), CH2 (235-344), CH3 N114>H (440) (345-451), CHS (452-453)) (119-453)], (133-217')-disulfide with kappa light chain caninized (1'-217') [V-KAPPA (Canis lupus familiaris IGKV3-18*02 (85.1%) -IGKJ3*01 (91.7%), CDR-IMGT [10.3.9] (27-36.54-56.93-101)) (1'-111') -Canis lupus familiaris IGKC*01 (100%) (112'-217')]; dimer (230-230'':233-233'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-derived cell line transfected with the glutamine synthetase (GS) gene, glycoform alfa
Структура
Иностранные названия
- Riltovetbartum (латинское)
- Riltovetbart (английское)
- Riltovetbart (немецкое)
- Riltovetbart (французское)
- Riltovetbart (испанское)
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