Римтеравимаб
RimteravimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2540797-21-3
Химическое название
immunoglobulin gamma1 VH-h-CH2-CH3 dimer, anti- [receptor binding domain (RBD) of the spike (S) glycoprotein of severe acute respiratory syndrome coronavirus (SARS-CoV) / severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) / bat SARS- like (bat) coronavirus WIV1 (bat SL-CoV-WIV1)], monoclonal antibody, bivalent;
gamma1 VH-h-CH2-CH3 chain (1-361) [VH Vicpac/Homsap (Vicugna pacos IGHV3-3*01 R50 (45) (93.8%) -(IGHD) -IGHJ3*01 (92.3%)/Homo sapiens IGHV3-23*04 (83.5%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.18] (26-33.51-58.97-114)) (1-125)] -10 mer bis(tetraglycyl-seryl) linker (126-135) -[Homo sapiens IGHG1*01 h-CH2-CH3, G1m17, G1v14 CH2 A1.3, A1.2 (hinge 6-15 (136-145), CH2 L1.3>A (149), L1.2>A (150) (146-255), CH3 D12 (271), L14 (273) (256-360), CHS K>del (361)) (136-361)], dimer (141- 141'':144-144'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-DG44 cell line, glycoform alfa
gamma1 VH-h-CH2-CH3 chain (1-361) [VH Vicpac/Homsap (Vicugna pacos IGHV3-3*01 R50 (45) (93.8%) -(IGHD) -IGHJ3*01 (92.3%)/Homo sapiens IGHV3-23*04 (83.5%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.18] (26-33.51-58.97-114)) (1-125)] -10 mer bis(tetraglycyl-seryl) linker (126-135) -[Homo sapiens IGHG1*01 h-CH2-CH3, G1m17, G1v14 CH2 A1.3, A1.2 (hinge 6-15 (136-145), CH2 L1.3>A (149), L1.2>A (150) (146-255), CH3 D12 (271), L14 (273) (256-360), CHS K>del (361)) (136-361)], dimer (141- 141'':144-144'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-DG44 cell line, glycoform alfa
Структура
Иностранные названия
- Rimteravimabum (латинское)
- Rimteravimab (английское)
- Rimteravimab (немецкое)
- Rimtéravimab (французское)
- Rimteravimab (испанское)
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