Ривабазумаб пэгол
Rivabazumab pegolМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
1613506-32-3
Химическое название
immunoglobulin Fab' G1-kappa pegylated, anti- [Pseudomonas aeruginosa type III secretion system (TTSS) PcrV protein], pegylated humanized monoclonal antibody;
gamma1 heavy chain fragment VH-(CH1-hinge) (1-238) [humanized VH (Homo sapiens IGHV3-30*06 (92.90%) - (IGHD)-IGHJ6*01) [8.8.17] (1-124) -Homo sapiens IGHG1*01 (CH1 (125-222), hinge C5>S (227) (223-237), CH2 (238)) (125-238)], noncovalently associated with kappa light chain (1’-214’) [humanized V-KAPPA (Homo sapiens IGKV1-5*01 (84.60%) -IGKJ2*01) [6.3.9] (1'-107') - Homo sapiens IGKC*01 C126>S (214') (108'-214')]; conjugated via a linker of the maleimide group (thioether bond with cysteinyl H h 11 (C233) and H h 14 (236)) to two linear chains of methoxy polyethylene glycol 30 (mPEG30).
gamma1 heavy chain fragment VH-(CH1-hinge) (1-238) [humanized VH (Homo sapiens IGHV3-30*06 (92.90%) - (IGHD)-IGHJ6*01) [8.8.17] (1-124) -Homo sapiens IGHG1*01 (CH1 (125-222), hinge C5>S (227) (223-237), CH2 (238)) (125-238)], noncovalently associated with kappa light chain (1’-214’) [humanized V-KAPPA (Homo sapiens IGKV1-5*01 (84.60%) -IGKJ2*01) [6.3.9] (1'-107') - Homo sapiens IGKC*01 C126>S (214') (108'-214')]; conjugated via a linker of the maleimide group (thioether bond with cysteinyl H h 11 (C233) and H h 14 (236)) to two linear chains of methoxy polyethylene glycol 30 (mPEG30).
Структура
Иностранные названия
- Rivabazumabum pegolum (латинское)
- Rivabazumab pegol (английское)
- Rivabazumab pegol (немецкое)
- Rivabazumab pégol (французское)
- Rivabazumab pegol (испанское)
Подробнее по теме
Узнайте дополнительные сведения о действующем веществе Ривабазумаб пэгол: