Рокатинлимаб
RocatinlimabМНН
Rec. INN (наименование, зарегистрированное ВОЗ)
CAS
2431972-52-8
Химическое название
immunoglobulin G1-kappa, anti-[Homo sapiens TNFRSF4 (tumor necrosis factor receptor (TNFR) superfamily member 4, OX40, CD134)], Homo sapiens monoclonal antibody;
gamma1 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV2-5*02 (94.0%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [10.7.9] (26-35.53-59.98-106)) (1-117) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (214) (118-215), hinge 1-15 (216-230), CH2 (231-340), CH3 D12 (356), L14 (358) (341-445), CHS (446-447)) (118-447)], (220-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV3-20*01 (98.9%) -IGKJ4*01 (100%), CDR-IMGT [7.3.8] (27-33.51-53.90-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (226-226'':229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
gamma1 heavy chain Homo sapiens (1-447) [VH (Homo sapiens IGHV2-5*02 (94.0%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [10.7.9] (26-35.53-59.98-106)) (1-117) -Homo sapiens IGHG1*01 (100%), G1m17,1 (CH1 K120 (214) (118-215), hinge 1-15 (216-230), CH2 (231-340), CH3 D12 (356), L14 (358) (341-445), CHS (446-447)) (118-447)], (220-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV3-20*01 (98.9%) -IGKJ4*01 (100%), CDR-IMGT [7.3.8] (27-33.51-53.90-97)) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214')]; dimer (226-226'':229-229'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
Структура
Иностранные названия
- Rocatinlimabum (латинское)
- Rocatinlimab (английское)
- Rocatinlimab (немецкое)
- Rocatinlimab (французское)
- Rocatinlimab (испанское)
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