Роконкибарт

Rec. INN (наименование, зарегистрированное ВОЗ)

immunoglobulin G4-kappa, anti-[Homo sapiens IL17A (interleukin 17A, IL-17A)], monoclonal antibody;
gamma4 heavy chain (1-444) [VH (Homo sapiens IGHV1-2*02 (85.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.10] (26-33.51-58.97-106)) (1-117) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (118-215), hinge 1-12 S10>P (225) (216-227), CH2 L92 (306) (228-337), CH3 (338-442), CHS (443-444)) (118-444)], (131-219')-disulfide with kappa light chain (1'-219') [V-KAPPA Musmus/Homsap (Mus musculus IGKV1-110*01 (92.0%) -IGKJ2*03 (91.7%) S120>Q (105)/Homo sapiens IGKV2-30*02 (88.0%) -IGKJ2*01 (100%), CDR-IMGT [11.3.9] (27-37.55-57.94-102)) (1'-112') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (223-223'':226-226'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa

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